Welcome to HALOmem!

HALO ← city of Halle ←  ἅλας (greek: salt)
mem ← membrane

HALOmem is an interdisciplinary research center at the University of Halle (MLU). We focus on the structure of membrane proteins and their interactions with the surrounding membrane. HALOmem was founded as a joint effort of the Institute of Biochemistry & Biotechnology (Fakultät I) and the Institutes of Physics and Chemistry (Fakultät II). The research center brings together resources and special expertise from both Institutes, such as recombinant protein production, biophysical methods for studying membranes, and protein structure determination by crystallography and NMR. Within the first funding phase of the HALOmem research center (2009-2014), two independent tenure-track junior research groups were established:

Research Group I: Membrane Protein Biochemistry (Dr. Mikio Tanabe), now associate Professor at the Structural Biology Reseach Center, KEK, Japan)
Research Group II: Biophysical Chemistry of Membranes (Dr. Kirsten Bacia), now Professor of Biophysical Chemistry at the MLU; see also: Das Abenteuer Forschung, a portrait of Kirsten Bacia at “Unternehmen Region”)

Following the successful defense of its extended Strategy Paper, HALOmem was recently awarded funding for a further five years to expanding its expertise platform with the establishment of two new independent research groups, working and collaborating within the stimulating multidisciplinary environment that has established Halle as an internationally recognised centre for pure and applied protein biochemistry, biotechnology and biophysics.

Research Group IV “Biophysical Characterisation of Medically Relevant Membrane Proteins”
Dr. Carla Schmidt is establishing a team to analyse protein-lipid-interactions in synaptic vesicles and the neuronal synapse; see Aim of Research for an overview. Current open positions can be found under the setting “Jobs”. For further information, please contact Jun. Prof. Dr. Carla Schmidt (.(JavaScript must be enabled to view this email address)).


HALOmem and the German Federal Ministry of Education and Research (BMBF) seek a highly motivated and outstanding junior scientist for the tenure track position of:
Group Leader “Cryo-Electron Microscopy of Membrane Protein Complexes”
The successful candidate will establish a team to study membrane protein complexes using cryo-electron microscopy (single particle reconstruction and/or tomography). The applicant will have trained in membrane protein biochemistry and/or cryo-EM, with documented experience at postgraduate and postdoctoral level. The candidate will have unrestricted access to the 300 kV JEOL JEM-3200FSC (equipped with field emission gun, cryo-stage, in-line energy filter and GATAN K2 direct electron detector) that is presently being installed.
Please note that there are special requirements attached to the application.


HALOmem is supported by the federal Zentrum für Innovationskompetenz (ZIK, Center for Innovation Competence) initiative of the Bundesministerium für Bildung und Forschung (BMBF) and by the state of Sachsen-Anhalt.