Research

Rainer Rudolph †

The Rudolph lab studies membrane proteins which occupy key positions in the communication between the extracellular and the intracellular space and attract pharmaceutical interest as therapeutic targets. Main research targets are for instance G-protein-coupled receptors (GPCRs) of class B, GPCRs of class A and carriers for organic solutes.

Institute of Biochemistry and Biotechnology

We are saddened by the unexpected death of Prof. Rainer Rudolph in December 2009.

Alfred Blume

Curriculum Vitae [pdf]

Blume lab at the Institute of Chemistry

Prof. Blume´s research interests:
Self-assembly of amphiphilic molecules: micelles, nanofibers and nanoparticles, lyotropic phases, monomolecular films at interfaces, biological model membranes.
Structure and dynamics of amphiphilic molecules: x-ray scattering on lyotropic systems, thermodynamic investigations with calorimetric methods (DSC, ITC), spectroscopic investigations using NMR-, FT-IR-, Raman-spectroscopy, FT-IR-reflection spectroscopy at interfaces, kinetics of phase transitions in lyotropic systems (stopped-flow-technique, pressure jump methods with UV-Vis, IR, light scattering and NMR detection).
Interactions of peptides and proteins with monolayers and model membranes: calorimetry (ITC, DSC) on lipid-protein-vesicles, FT-IR-spectroscopy of lipid-protein-vesicles and solid supported membranes, FT-IR-reflection-absorption-spectroscopy (IRRAS) on monomolecular films of lipids and proteins at the air-water interface, AFM of solid supported membranes